recurrent / metastatic head and neck squamous cell carcinoma
Conditions
Interventions
Sponsors
The fourth affiliated hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. aged 18-70 years old; 2. head and neck tumor histologic diagnosis of squamous cell carcinoma; 3. pathology or clinical diagnosis of recurrence and distant metastasis, after at least one treatment of disease progress; 4. ECoG score=2; 5. is expected to life expectancy over 6 months; 6. without strict Center Department of pulmonary disease; 7. meet the following clinical laboratory standards: all indexes of liver and kidney function were in the upper limit of the normal value of 1. 5 times the range, the ANC is more than or equal to 1.5*10^9/L, PLT is equal to or larger than 80*10^9/L; 8. Signed informed consent forms.
Exclusion criteria
Exclusion criteria: 1) cognitive impairment. 2) combined with other cancer patients. 3) patients with contraindications: Aitan allergic to any ingredients should be disabled for active bleeding, ulcers, intestinal perforation, intestinal obstruction, after major surgery within 30 days, uncontrollable high blood pressure drugs, 3-4 heart failure (NYHA standards), severe liver and kidney dysfunction (level 4). 4) bleeding (except local bleeding) or coagulation abnormalities (APTT>1.5xULN or INR>1.5). 5) specialist antihypertensive treatment for poorly controlled high blood pressure (specialist treatment case systolic pressure >180mmHg and/or diastolic pressure >100mmHg). 6) Kidney Foundation disease with protein in the urine. 7),pregnancy, lactation, or fertile but not contraceptives for women. 8) drug or alcohol addicts. 9)Other researchers believe that patients with inappropriate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression-free survival;hematological toxicity;Non-hematological toxicity; | — |
Secondary
| Measure | Time frame |
|---|---|
| overall survival;Disease remission rate;quality of life; | — |
Countries
China
Contacts
Public ContactLu Ying
The fourth affiliated hospital of Guangxi Medical University
Outcome results
None listed