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A study of neurological basis for dysfunction of mood and cognition in hyperthyroid patients: a resting-state fMRI study

A study of neurological basis for dysfunction of mood and cognition in hyperthyroid patients: a resting-state fMRI study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OOC-16008607
Enrollment
Unknown
Registered
2016-06-07
Start date
2016-07-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperthyroidism

Interventions

2:none

Sponsors

Department of Psychosomatics and Psychiatry, Zhongda Hospital, School of Medicine, Southeast University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Hyperthyroidism Group: (1) Patients having elevated FT3 levels,FT4 levels and TSH levels; (2) Patients aged between 18-70 years; (3) Patients with education level over 9 years; (4) Patients having ability to understand the study; (5) Right handedness. Healthy Control Group: (1) Controls with normal FT3, FT4 and TSH levels; (2) Controls having no significant difference in age, sex and education compared to hyperthyroidism group; (3) Controls having no significant difference in demographics data compared to hyperthyroidism group; (4) Right handedness.

Exclusion criteria

Exclusion criteria: (1) A history of neurological or psychiatric illness, including head injury, cerebral hemorrhage, major depression and so on; (2) Drug or alcohol abuse history; (3) A history of cardiovascular or pulmonary diseases that affected BOLD fluctuations; (4) Contraindications to MRI scanning; (5) Participating in other researches.

Design outcomes

Primary

MeasureTime frame
FT3;FT4;TSH;TRAb;TPOAb;TGAb;BOLD-fMRI;3D;DTI;VBM;

Countries

China

Contacts

Public ContactYuan Yonggui

Zhongda Hospital, School of Medicine, Southeast University

yygylh2000@sina.com+86 13913939082

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 23, 2026