postoperative cognitive dysfunction
Conditions
Interventions
Case series:NA
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
50 Years to 100 Years
Inclusion criteria
Inclusion criteria: Patients aged more than 50 years presenting for major cardiac surgery in West China Hospital, Sichuan University.
Exclusion criteria
Exclusion criteria: Mini-Mental State Examination (MMSE) scores less than 17 (illiterati), less than 20 (patients with primary education), less than 24(patients with secondary and higher educations); disease of the central nervous system; were taking tranquillisers or antidepressants; had underwent neurological or cardiac surgery; previously underwent neuropsychological testing; were unwilling to comply with the protocol or procedures; had any severe visual or auditory disorders; alcoholism, or drug dependence; were not expected to be discharged alive from hospital after surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| circulating RNA; | — |
Secondary
| Measure | Time frame |
|---|---|
| inflammatory cytokines; | — |
Countries
China
Contacts
Public ContactChen Chan
West China Hospital, Sichuan University
Outcome results
None listed