polycystic ovary syndrome (PCOS)
Conditions
Interventions
Three groups: Ovulatory PCOS patients versus ovulatory fertile controls versus non-ovulatory subjects:Endometrial biopsy and peripheral blood will be obtained from women with PCOS and from controls, e
Sponsors
The Chinese University of Hong Kong
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Infertile PCOS women with age < 40 undergoing assisted reproductive technology (ART) treatment. The diagnosis of PCOS is based on the Rotterdam criteria (2003), briefly: 2 out of 3 criteria after exclusion of other aetiologies. 1) Oligo-amenorrhoea/ chronic anovulation; 2) Clinical and/or biochemical hyperandrogenism; 3) Ultrasound features of polycystic ovaries
Exclusion criteria
Exclusion criteria: (1) Uncorrected uterine pathologies such as congenital uterine anomalies, intrauterine adhesions, adenomyosis, fibroids, endometrial polyp; (2) Hydrosalpinx
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Transcriptome in endometrium in day 7 after LH surge, and transcriptomes in perpheral blood of different time points.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hormone levels and pregnancy outcomes of ART patients; | — |
Countries
China
Contacts
Public ContactLai-ping Cheung
Department of Obsterics & Gynaecology, The Chinese University of Hong Kong
Outcome results
None listed