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A prospective study of predictive markers of chemotherapy-related amenorrhea in premenoposual breast cancer patients

A prospective study of predictive markers of chemotherapy-related amenorrhea in premenoposual breast cancer patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OOC-16008104
Enrollment
Unknown
Registered
2016-03-16
Start date
2016-04-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

premenopausal breast cancer patient:none

Sponsors

The Third Affiliated Hospital of GuangZhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. To be with primary operable breast cancer without evidence of metastases; 2. being premenopausal assessed by regular menses; 3. plant to receive standard adjuvant chemotherapy with cyclophosphamide,and 4. sign written informed consent.

Exclusion criteria

Exclusion criteria: 1. ovary tumor or salpingoophorectomy or hysterectomy or pelvic radiation prior to the follow-up; 2. history of prior chemotherapy; 3. pregnancy; 4. undergone ovarian suppression.

Design outcomes

Primary

MeasureTime frame
antimullerian hormone;follicle-stimulating hormone;inhibin B;—

Secondary

MeasureTime frame
antral follicle counts;estradiol;—

Countries

China

Contacts

Public ContactJuan Huang

The Third Affiliated Hospital of GuangZhou Medical University

huangjuan777777@163.com86 13697433377

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026