Epithelial Ovarian Cancer
Conditions
Interventions
Case series:Apatinib MesylateTablets 500mg or 750mg(depend on BSA) Qd
Sponsors
Changhai Hospital Affiliated to The Second Military Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Epithelial ovarian carcinoma diagnosed by histologic or cytological test; 2. Aged 18 to 75 years; 3. Recurrent after standard treatment or no respond to chemotherapy; 4. 0-2 scores of Eastern Cooperative Oncology Group (ECOG); 5. an estimated life expectancy of at least 3 months; 6. HB>=90g/L, ANC>=1.5×10^9/L, PLT>=80×10^9/L; 7. adequate liver and kidney function.
Exclusion criteria
Exclusion criteria: 1. severe hypertension; 2. Have the disease influencing oral drug absorption, such as unable to swallow, chronic diarrhea and intestinal obstruction; 3. contraindications for Apatinib MesylateTablets; 4. mental disease; 5. allergies to any components of the study drug; 6. concurrent any other clinical and biochemical test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ORR(Objective Response Rate);DCR(Disease Control Rate); | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life;Ovarian cancer symptoms; | — |
Countries
China
Contacts
Public ContactChaoqin Yu
Outcome results
None listed