postoperative pain
Conditions
Interventions
Case series:remifentani and sufentani
Sponsors
Anesthesiology of Zhujiang Hospital of Southern Medical University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. The age of 18-60 years old; 2. American Society of anesthesiologists (ASA) grade I or II grade; 3. Undergoing elective gynecologic laparoscopic surgery; 4. Agree to receive postoperative sufentanil analgesia pump for 48 hours. No serious cardiovascular disease, normal liver and kidney function; 5. Have not received chemotherapy treatment.
Exclusion criteria
Exclusion criteria: 1. allergies or allergic reaction to the drug used during perioperative period; 2. The long-term use of sedative and analgesic drugs or have a history of chronic pain; 3. Patients with depression and other mental dysfunction; 4. Taking known to inhibit or elevated enzymes CYP3A4 expression of drug (1 week) or food (3 days): erythromycin, clarithromycin, alcohol, chocolate, coffee, grapefruit, different verapamil, rifampicin, HIV protease inhibitors, phenytoin Britain, itraconazole, dexamethasone and phenobarbital, carbamazepine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| COMTvall58met, OPRMI A118G and CYP3A4; | — |
Countries
China
Contacts
Public ContactXu Shiyuan
Outcome results
None listed