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The effect of blastomere loss during frozen embryo transfer on IVF outcome and offspring's health

The effect of blastomere loss during frozen embryo transfer on IVF outcome and offspring's health and the underlying mechanism

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OOC-16007753
Enrollment
Unknown
Registered
2016-01-13
Start date
2005-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

blastomere loss during frozen embryo transfer

Interventions

Case series:frozen-thawed embryo

Sponsors

the International Peace Maternity and Child Health Hospital of China welfare Institute
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 14 Years

Inclusion criteria

Inclusion criteria: According to the survival after cryopreservation, transferred embryos were split into two groups: transfers with all embryos having lost at least one blastomere (damage group) and transfers with all embryos intact (intact group).

Exclusion criteria

Exclusion criteria: FET with both damage embryo and intact embryo.

Design outcomes

Primary

MeasureTime frame
pregnancy rate;birth weight;Gesell Developmental Schedules;Chinese Wechsler Intelligence Scale;RNA-Seq transcriptome of offspring’s umbilical cord blood;—

Countries

China

Contacts

Public ContactHefeng Huang
huanghefg@hotmail.com+86 13906526300

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 6, 2026