acute coronary syndrome
Conditions
Interventions
the cohort of Integrated Chinese Western medicine treatment with invigourating spleen to reduce phlegm , dissipating blood stasis relieving internal pathogenic factors methods:Integrated Chinese Weste
the cohort of Integrated Chinese Western medicine treatment with invigourating spleen to reduce phlegm promoting blood circulation to dissipating blood stasis:Integrated Chinese Western medicine treat
the cohort of Western medicine:Western standard treatment
Sponsors
The Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients will be eligible to participate if they are: 1. Comply with unstable angina or non ST segment elevation acute myocardial infarction by diagnostic criteria of Western Medicine,with?thoracic obstruction,phlegm turbidity syndrome result spleen deficiency by diagnostic criteria of traditional Chinese Medicine; 2. Admitted within 72 hours since the on; 3. Aged 40-75 years 4. Can provide a detailed contact information,no short-term transfer,able to coordinate follow-up; 5. Voluntary participation in clinical observation signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Have got infections, fever, trauma, burn, inflammation surgery happened or inflammatory drugs antibiotics have been taken in the past 1 months; 2. Treated with thrombolysis emergency interventional therapy, history of coronary artery bypass grafting within 3 months or history of percutaneous coronary intervention within 6 months; 3. Combined with severe heart failure (class IV of heart function), malignant arrhythmia. 4. Hypertension higher than 160/100mmHg within standard anti-hypertensive therapy; 5. Have a history of bleeding cerebral blood vessel accident,or have a of ischemic stroke (including TIA) history within six months; 6. Combined with other serious tem diseases (malignant tumor, gastrointestinal hemorrhage, gastric ulcer, hemorrhagic cerebrovascular accident, so on) function examination of liver kidney (more than 1.5 times the reference value of aspartate aminotransferase (AST), alanine tranminase (ALT), creatinine(Cr)); 7. Pregnant, breast-feeding or preparing for pregnancy; 8. Allergic constitution or Chinese medicine granule allergy; 9. In the past 4 weeks, taken Chinese traditional medicine preparation for the study of drugs have similar effects; 10.may not be able to understthe requirements of the program for some reasons such as mental illness, the degree of culture, language barrier so on; 11. enrolled in other clinical trials within two months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Re-admission for ischemic chest pain;ST segment elevation acute myocardial infarction;Reconstruction of blood supply;All due to death; | — |
Secondary
| Measure | Time frame |
|---|---|
| hypersensitive C-reactive protein;interleukin-6;interleukin-10;Matrix Metalloproteinase-9;tissue inhibitor of metalloproteinase-1;Angina score;Seattle Angina Questionnaiire; | — |
Countries
China
Contacts
Public ContactZhang Zhe
Outcome results
None listed