bronchial asthma
Conditions
Interventions
lean asthma group (stable):no intervention
overweight/obese asthma group (stable):no intervention
lean asthma group (acute):no intervention
overweight/obese asthma group (acute):no intervention
Sponsors
Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
20 Years to 69 Years
Inclusion criteria
Inclusion criteria: adult patients with brochial asthma diagonized according to GINA (2012)
Exclusion criteria
Exclusion criteria: Stable asthma patients should have no asthma exacerbation, respiratory tract infection or systemic corticosteroid use in the preceding 4 weeks and are not accompanied by parenchymal lung disease apparent on chest radiography, diabetes mellitus, cardiovascular disease, pregnancy, autoimmune diseases and tumors. Patients, in whom sputum induction could not be achieved, were also excluded. Acute asthma patients, who need endotracheal intubation or tracheostomy and mechanical ventilation and in whom sputum induction could not be achieved are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sputum neutrophil percentage;sputum eosinophil percentage;sputum IL-17 concentration;plasma IL-17 concentration; | — |
Secondary
| Measure | Time frame |
|---|---|
| forced expiratory volume in 1 second;forced vital capacity;asthma control questionnaire score;inhaled corticosteroid dose;Beck Depression Inventory II score;proportion of patients with obstructive sleep apnea;proportion of patients with gastro-esophageal reflux;proportion of patients with neutrophilic asthma;proportion of patients with eosinophilic asthma;pulse;respiratroy rate;arterial oxygen saturation; | — |
Countries
China
Contacts
Public ContactHu Chenping
Outcome results
None listed