Premature Ejaculation
Conditions
Interventions
Penile sensory hyperexcitability group:Compound Lidocaine Cream
Sympathetic hyperexcitability Group:Priligy(Dapoxetine)
Mixed type group :Compound Lidocaine Cream+Priligy(Dapoxetine)
Sponsors
Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical School
Eligibility
Sex/Gender
Male
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Male aged between 18 and 60; 2. Men in stable heterosexual, monogamous relationships >6 months; 3. Symptom of PE: in recent 6 months, ejaculation that always or nearly always occurs prior to or within about 2 minute of vaginal penetration; the inability to delay ejaculation; and negative personal consequences, such as distress, bother, frustration, and/or the avoidance of sexual intimacy.
Exclusion criteria
Exclusion criteria: 1. Urinary system infection: Abnormal result of routine urine and prostatic fluid routine examination; 2. Abnormal sex hormone: Abnormal result of sex hormone examination; 3. Systemic disease: hypertension, diabetes mellitus, alcohol dependence syndrome, coronary heart disease, and Mental disorder; 4. Organic disorder: Abnormal palpation of external genitals, testis, epididymis and spermatic cord; 5. Drug influence: use of any drug for PE, e.g. SSRI , PDE-5, tramadol, etc; 6. Known drug allergy to amide-type local anaesthetics or dapoxetine; 7. Currently participating, or in the past 30 days quit a another clinical research independent with this research; 8. Drugs, alcohol or substance abuse in last 6 months; 9. moderate or more severe erectile Dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intravaginal ejaculation latency time;PEDT;PEP; | — |
Countries
China
Contacts
Public ContactYutian Dai
Outcome results
None listed