chronic heart failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. A history of heart failure. The signs or symptoms of heart failure, left ventricular ejection fraction (left ventricular ejection fraction, LVEF) 45%, but there are echocardiographic evidences of left ventricular diastolic dysfunction; 2. Aged from 65 to 80 years; 3. Class I–III cardiac function (NYHA); 4. BP (with or without drug control) less than 150/90mmHg.
Exclusion criteria
Exclusion criteria: 1. Catching a cold and other acute diseases two weeks prior to the trial or during the trial process; 2. Chronic history including cancer, serious liver, kidney, brain, heart, lung diseases, etc.; 3. Acute myocardial infarction in previous three months or cerebrovascular accident within six months or exper iencing a severe trauma or a major surgery; 4. Incapable of taking care of themselves in daily life.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BNP; | — |
Secondary
| Measure | Time frame |
|---|---|
| BP;P;echocardiography factor;endothelin-1;ACE;AT1R;AT2R;type I procollagen;TNF-a;IL-6;CRP;ADL;ambulation capacity; | — |
Countries
China