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The impact of obstructive sleep apnea in patients with chronic obstructive pulmonary disease: Biomarkers of hypoxemia and cardiovascular events

The impact of obstructive sleep apnea in patients with chronic obstructive pulmonary disease: Biomarkers of hypoxemia and cardiovascular events

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OOC-15006691
Enrollment
Unknown
Registered
2015-07-02
Start date
2015-07-06
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obstructive sleep apnea, COPD

Interventions

Case series:Nil

Sponsors

Yen Tjing Ling Medical Foundtion
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Male or female outpatients aged from 40 to 90 years; 2. History of cigarette smoking over than 10 pack-years; 3. Stable COPD patients without exacerbation 3 months prior to recruitment; 4. OSA patients without continuous positive airway pressure treatment for at least 3 months; 5. Agree to attend study and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Clinically overt bronchiectasis, lung cancer, active tuberculosis, or other known specific pulmonary disease and a chest X-ray indicating diagnosis other than COPD that might interfere with the study; 2. Suspected or proven thromboemolic diseases, such as cerebral or myocardial infaction, pulmonary embolism, deep vein thrombosis, etc.; 3. Patients with significant cardiovascular disease (ischemic heart disease, vascular heart disease, cardiomyopathy, aortic aneurysm, heart failure); 4. Patients received systemic steroid 4 weeks prior to the commencement of study.

Design outcomes

Primary

MeasureTime frame
HIF-1;IL-6;C-reactive protein;Fibrinogen;D-dimer;NT-pro-BNP;lung function;Apnea-Hyponea-index;

Countries

China

Contacts

Public ContactKang-Cheng Su
kcsu@vghtpe.gov.tw+886-2-28712121 ext 8928

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026