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Effect of propofol repeated anesthesia on congnitive function of developing brain in human and rat

Effect of propofol repeated anesthesia on congnitive function of developing brain in human and rat

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OOC-15006307
Enrollment
Unknown
Registered
2015-04-24
Start date
2015-05-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Cognitive Dysfunction

Interventions

one cohort:Non-Intervention

Sponsors

Department of Anesthesiology, Children's Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 14 Years

Inclusion criteria

Inclusion criteria: Participants will be deemed eligible if they are 0-14 years old,suffer from hypospadias, hydronephrosis or esophageal stenosis.

Exclusion criteria

Exclusion criteria: Congenital diseases: Congenital syndromes, Spina bifida, Congenital heart surgery, Osteogenesis imperfecta, Sickle cell anemia, Congenital psychomotor retardation; Events in medical history possibly related to cognitive impairment; Documented peripartum cerebral ischemia/hypoxic brain injury, Peripartum metabolic events (hypoglycemia, infection, seizures), Having been ventilated in a neonatal Intensive care Unit, Received high doses of corticosteroids, Malignancies; More than three comorbidities; Procedure-related; Children who have been adopted. Aged >14 years at moment of recruitment.

Design outcomes

Primary

MeasureTime frame
cognitive function scores;

Countries

China

Contacts

Public ContactShengfen Tu
519194496@qq.com+86 13983416144

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026