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Airway inflammation and clinical characteristics of different subtypes of asthma

Airway inflammation and clinical characteristics of different subtypes of asthma

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OOC-15006221
Enrollment
Unknown
Registered
2015-02-05
Start date
2015-03-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bronchial asthma

Interventions

Case series:Nil

Sponsors

Second Affiliated Hospital, Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. all subjects agreed to participate, understand the project, observe the use of drugs, agree to follow-up, and signed informed consent; 2. the age of more than 18 years old, gender and ethnicity are not limited; 3. With typical clinical manifestations of CTVA, CVA, and CA; 4. a diagnosis of asthma supported by one or more other characteristics: (1) bronchial provocation test positive; (2) improvement in FEV1 of more than 12% and 200 mL after inhaled salbutamol; (3) variability in diurnal peak expiratory flow (PEF) of more than 10% for one day during one week; 5. bronchodilator and glucocorticoid treatment is effective; 6. exclude the following diseases by the corresponding doctors: coronary heart disease, myocarditis, heart failure, GERD, neuromuscular disease, and mental disease.

Exclusion criteria

Exclusion criteria: 1. can not cooperate with related inspection or for other reasons; 2. patients with chronic obstructive pulmonary disease, interstitial pneumonia, active tuberculosis, community acquired pneumonia, lung cancer, bronchiectasis, cor pulmonale, pulmonary embolism, and companied with serious systematic disease (such as coronary heart disease, myocarditis, heart failure, GERD, neuromuscular disease, etc); 3. history of drug abuse, alcohol abuse or anesthesia or with a history of mental illness (schizophrenia, obsessive-compulsive disorder, depression) and against personality, motivation, suspicious, or other emotional or mental issues that may affect participation in the study; 4. taking part in other drug clinical trial project, or drop out less than 3 months; 5. during pregnancy, lactation women; 6. obvious abnormal of HRCT.

Design outcomes

Primary

MeasureTime frame
cytokines;

Contacts

Public ContactHuahao Shen
huahaoshen@163.com+86 0571-88981915

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 26, 2026