bronchial asthma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. all subjects agreed to participate, understand the project, observe the use of drugs, agree to follow-up, and signed informed consent; 2. the age of more than 18 years old, gender and ethnicity are not limited; 3. With typical clinical manifestations of CTVA, CVA, and CA; 4. a diagnosis of asthma supported by one or more other characteristics: (1) bronchial provocation test positive; (2) improvement in FEV1 of more than 12% and 200 mL after inhaled salbutamol; (3) variability in diurnal peak expiratory flow (PEF) of more than 10% for one day during one week; 5. bronchodilator and glucocorticoid treatment is effective; 6. exclude the following diseases by the corresponding doctors: coronary heart disease, myocarditis, heart failure, GERD, neuromuscular disease, and mental disease.
Exclusion criteria
Exclusion criteria: 1. can not cooperate with related inspection or for other reasons; 2. patients with chronic obstructive pulmonary disease, interstitial pneumonia, active tuberculosis, community acquired pneumonia, lung cancer, bronchiectasis, cor pulmonale, pulmonary embolism, and companied with serious systematic disease (such as coronary heart disease, myocarditis, heart failure, GERD, neuromuscular disease, etc); 3. history of drug abuse, alcohol abuse or anesthesia or with a history of mental illness (schizophrenia, obsessive-compulsive disorder, depression) and against personality, motivation, suspicious, or other emotional or mental issues that may affect participation in the study; 4. taking part in other drug clinical trial project, or drop out less than 3 months; 5. during pregnancy, lactation women; 6. obvious abnormal of HRCT.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cytokines; | — |