Allergy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Written informed consent obtained before entering the trial; 2. Male or female to be aged 5 to 55 years old; 3. Have accepted house dust mite specific subcutaneous immunotherapy for 3 years,and the discontinued treatment period was not over 6 months; 4. With good compliance.
Exclusion criteria
Exclusion criteria: 1. Participate in other clinical drug trials in 3 months; 2. A clinical history of COPD; 3. More than 10 pack years of smoking history; 4. Any of the following underlying conditions known or suspected to be present: Cystic fibrosis, malignancy, insulin-dependent diabetes, malabsorption or malnutrition, renal, or hepatic insufficiency, chronic infection or with any evidence of disease making implementation of the protocol or interpretation of the protocol results difficult or jeopardising the safety of the patient (e.g. clinically significant cardiovascular, serious immunopathologic, immunodeficiency whether acquired or not, hepatic, neurologic, psychiatric, endocrine, or other major systemic disease); 5. History in the previous 4 weeks of exacerbations of asthma(systemic corticosteroids use for asthma or need for emergency or hospitalization.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| symptom score and drug score;specific IgE;specific IgG4;T-reg cell; | — |
Countries
China