sleep disorders
Conditions
Interventions
Case series:Nil
Sponsors
Second Military Medical University Affiliated Changzheng Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. To be aged between 40-75 years old (male vs. female ratio 1: 1); 2. in line with the diagnostic criteria for chronic renal failure, each stage can be; 3. who has complained of sleep disorders, and PSQI score> 5 points included in the case group and the control group included the rest; 4. neurological examination no signs, no previous psychiatric history and the history of central nervous system diseases; 5. no other serious medical system history, including but not limited to: coronary heart disease, cardiomyopathy, serious, severe valvular heart disease, uncontrolled hypertension, uncontrolled diabetes, chronic heart failure, chronic respiratory failure, severe emphysema, severe lung infection, severe hepatitis; 6. subjects himself or authorized client signed informed consent; 7. to be able to cope with the completion of the inspection, compliance is good.
Exclusion criteria
Exclusion criteria: 1. previous history of central nervous system diseases or clear history of mental illness, including, but not limited to, cerebral infarction, cerebral hemorrhage, subarachnoid hemorrhage, central nervous system infections, Parkinson's disease, dementia, epilepsy, depression, anxiety, schizophrenia, mania, bipolar disorder; 2. there is an obvious other abnormal laboratory parameters: liver function (ALT, AST) more than 1.5 times the upper limit of the normal range, the presence of abnormal blood count, fasting blood glucose more than 1.5 times the upper limit of the normal range; 3. uncontrolled blood pressure, systolic blood pressure greater than or equal to check 160mmHg or less than 90mmHg, or diastolic blood pressure greater than or equal to 100mmHg or less than 60mmHg; 4. the presence of unstable or severe heart, lung, liver, blood system diseases; 5. can not complete polysomnography, sympathetic stimulation test examination, can not scale with the completion of the evaluation, can not cope with specimens of blood, urine samples; 6. alcohol or drug abuse abusers; 7. the researchers believe that the subject can not complete the study; 8. refused to sign the informed consent; 9. stakeholders, researchers and investigators relatives exist.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sympathetic skin response;Urine osmolality;Urinary electrolyte;Urinary dopamine;Urinary melatonin;Cortisol;renin;angiotensin;Pittsburgh Sleep Quality Index Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Polysomnography; | — |
Countries
China
Contacts
Public ContactHe Bin
Outcome results
None listed