acute coronary syndrome
Conditions
Interventions
Sponsors
Peking university third hospital cadiology department
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.ST-Segment Elevation Myocardial Infarction (STEMI) group:(1)Age 18-80 years old; (2)Diagnosis of STEMI by the physicians on the basis of WHO criteria formulated in 1979; (3)Within 24 hours of symptom onset; (4)Written informed consent by the patient or surrogate. 2.Non ST-segment elevation myocardial infarction (NSTEMI) group:(1)Age 18-80 years old; (2)Clinical history of ischemic type chest pain lasting for more than 30 minutes;(3)Changes of serum cardiac biomarkers(CK-MB or troponin) (4)Changes in serial ECG tracings without ST-segment elevation Within 24 hours of symptom onset; (5)Written informed consent by the patient or surrogate 3. Unstable angina (UA) group:(1)Age 18-80 years old; (2)Ischemic chest pain occurring at rest or with minimal exertion, rapid deterioration of previously stable angina (crescendo pattern - more severe, prolonged or frequent than previously), or new onset severe ischemic chest pain of less than one month's duration; (4)Ischemic chest pain persists less than 30 minutes, ECG may be normal or may found ST-segment depression or T-wave inversion; (5)Serum cardiac biomarkers is normal Within 24 hours of symptom onset; (6)Written informed consent by the patient or surrogate.
Exclusion criteria
Exclusion criteria: (1)Valvular heart disease or other structural heart disease; (2)Known cardiomyopathy; (3)Prior surgery or trauma within 1 month prior to admission; (4)History of cerebrovascular disease in the past 6 months; (5)Malignancy; (6)Autoimmune disease; (7)Severe infection; (8)Severe hepatic or renal dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| epinephrine;norepinephrine;interleukin 18; | — |
Countries
china
Contacts
Public ContactXiao Han
Outcome results
None listed