Gastroesophageal Varices with Liver Cirrhosis
Conditions
Interventions
Gastroesophageal varices group:Test dynamic state of esophageal pH and pressure for 24 hours
Sponsors
Department of Gastroenterology, The Third Affiliated Hospital of Sun Yat-sen University.
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Male or female; 2. subjects 18 - 70 of age; 3. With history of liver cirrhosis, endoscopy prove gastroesophageal varices exist; 4. Without hepatic encephalopathy or other metal disorders; 5. Written informed consent.
Exclusion criteria
Exclusion criteria: 1. Hepatic encephalopathy or other metal disorders; 2. cavernous transformation of the portal vein,Budd-Chiari Syndrome and liver carcinoma; 3. With unstable vital signs; 4. Active bleeding patients; 5. With ACS, uncontrolled high blood pressure or other serious diseases; 6. Cannot reach written informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total acid reflux times in 24 hours;Number of upright acid reflux episode;Number of supine acid reflux episode;Duration of long reflux episode (>5min);Demester score;The resting pressure of inferior esophageal sphincte;The systolic pressure of inferior esophageal sphincter;The function of esophageal body peristalsis; | — |
Countries
China
Contacts
Public ContactBin Wu
Outcome results
None listed