Idiopathic pulmonary fibrosis
Conditions
Interventions
Montelukast Sodium Tablets treatment group :Montelukast Sodium Tablets: oral, 1 tablets each time (10mg), 1 time a day, at bedtime, for a period of 12 weeks
control group :Don't take Montelukast Sodium Tablets
Sponsors
Shanghai Pulmonary Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Idiopathic pulmonary fibrosis (IPF) patients are diagnosed according to the 2011 ATS / ERS /JRS / ALAT criterion; 2. patients with intractable cough, cough scores equal to or greater than 2; 3. Male or female; aged during 50 to 80 years old; 4. Have good compliance, willing to exercise in accordance with the program and follow-up with the schedule; 5. Patients were fully informed of the purpose, method and possible discomfort of the test, agree and signed in consent.
Exclusion criteria
Exclusion criteria: 1. With lung infections need antibiotic treatment; 2. patients with asthma; 3. patients with malignant tumor; 4. patients with serious diseases in other system and organ dysfunction; 5. Pregnancy, breast-feeding women, planning to pregnant and those who can not take effective contraceptive measures; 6. patients with obvious abnormal liver or kidney function, ALT or AST value greater than 1.5 times of normal; Cr value greater than 1.5 times of normal; 7. allergic to Montelukast Sodium Tablets; 8. Participating in other clinical trials within three months; 9. People who can't express discomfort; 10. There is any unsuitable situation for those selected.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cough score;Visual analogue scale;Efficiency evaluation; | — |
Contacts
Public ContactHuiping Li
Outcome results
None listed