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Assessment of Serum Free Cortisol in Septic patients: Relation to Adrenal Function, Cytokines and Outcome

Assessment of Serum Free Cortisol in Septic patients: Relation to Adrenal Function, Cytokines and Outcome

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OOC-15005821
Enrollment
Unknown
Registered
2015-01-13
Start date
2015-01-20
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Case series:Nil

Sponsors

Department of Geriatrics, Qi-Lu Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. meet the dignostic criteria of severs sepsis or septic shock published by Surviving Sepsis Campaign Guidelines Committee 2012; 2. To be aged 18 to 85; 3. patients or his/her family members sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. pregnant; 2. age beyond 85 or under 18; 3. patients or family members do not agree to participate in the trial; 4. taking steroids or other medicines that influence immune systems for more than 6 months; 5. co-exist serious organ disfunction due to other diseases rather than severe sepsis or septic shock; 6. end stage of malignant tumor or terminal illness; 7. HIV infection.

Design outcomes

Primary

MeasureTime frame
serum free cortisol;TNF-alpha;IL-6;TGF-beta;ACTH;28-day mortality;—

Countries

China

Contacts

Public ContactQian Cai
13573146645@163.com+86 13573146645

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026