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Comparison of C50 for propofol-remifentanil target-controlled Infusion and bispectral index at loss of consciousness and response to painful stimulus in elderly and young patients

Comparison of C50 for propofol-remifentanil target-controlled Infusion and bispectral index at loss of consciousness and response to painful stimulus in elderly and young patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OOC-14005629
Enrollment
Unknown
Registered
2014-11-19
Start date
2014-12-10
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

general anesthesia

Interventions

elderly:general anesthesia
young:general anesthesia

Sponsors

Beijing Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age older than 18yrs, Chinese patients; 2. Patients with medical conditions belongs to ASA I to II; 3. Did not take any sedation and/or opioid before induction; 4. Weight range from 80% to 120% of ideal body weight; 5. Have not serious diseases of heart, lung, brain, liver, kidney.

Exclusion criteria

Exclusion criteria: 1. Existed serious abnormal function of cardiovascular, respiratory,central nervous system, liver function, kidney function, endocrine system function; 2. Severe hypertension (SBP higher than 180mmHg; DBP higher than 110mmHg); 3. Long history of drinking and drug abuse; 4. Taken sedative hypnotic drugs recently.

Design outcomes

Primary

MeasureTime frame
predicted effect site concentration;predicted plasma concentration;Bispectral Index;consciousness;—

Secondary

MeasureTime frame
Heart rate;Blood pressure;Pulse oxygen saturation;—

Countries

China

Contacts

Public ContactNing Yang
yn_bjh@163.com+86 13810574264

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 2, 2026