atrial fibrillation
Conditions
Interventions
Case series:ablation
Sponsors
Shandong University/Qilu Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Age:18-75years; 2) presence of drug-refractory symptomatic paroxysmal or persistent AF as evidenced by 12-lead electrocardiogram (ECG) and 24h Holter monitoring; 3) absence of left atrial appendage/left atrium thrombus in TEE, or coronary CT examination if TEE is not tolerated; 4) left ventricular ejection fraction more than 30%; 5) left atrial diameter less than 55mm; 6) patient undergoing RFCA; and 7) agreed to participate in this study and complete follow-up by signing informed consent.
Exclusion criteria
Exclusion criteria: 1)Severe cardiomyopathy, valvular disease, congenital heart disease, decompensated heart failure and left ventricular dysfunction; 2) malignant tumors, acute or chronic infection, hyperthyroidism, connective tissue disease, liver and kidney dysfunction, poor control of blood pressure; 3) history of acute cardiovascular and cerebrovascular events, trauma or surgery within three previous months; 4) on immunosuppressive therapy and with low numbers of white blood cells; 5) reversible atrial fibrillation caused by thyroid hyperfunction, alcohol drinking, surgery or other causes; 6) failed ablation or severe post-ablation complications; 7) patient with contraindications to anti-coagulation; 8) pregnant or breast-feeding women; or 9) participation in other clinical research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Atrial fibrillation vulnerability; | — |
Countries
China
Contacts
Public ContactJing-quan Zhong
Outcome results
None listed