Lung cancer mediated malignant pleural effusion
Conditions
Interventions
None listed
Sponsors
Shandong University, School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Advanced lung cancer confirmed histologically or pathologically; 2. Ultrasonography or CT scan showing plural effusion and malignant tumor cells found in the pleural fluid; 3. To be aged older than 18 years; 4. All subjects or their guardians must sign an informed consent before entering the trial.
Exclusion criteria
Exclusion criteria: 1. Lung cancer patients with indications for surgery; 2. Patients with thrombocytopenia or coagulation disorders; 3. Major organ dysfunction, such as heart,liver, kidney or lung; 4. Under current treatment with targeted agents; 5. Are allergic to lobaplatin or erythromycin.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total efficiency (The total efficiency was calculated by taking the sum of CR+PR); | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression free survival (PFS);Objective response rate (ORR);Overall survival (OS);Qualify of Life was evaluated by the Kanofsky score (KPS);Level of chronic dyspnea will be assessed using modified Medical Research Council dyspnea scale (MMRC);Adverse events (AEs); | — |
Countries
China
Contacts
Public ContactLi Yu
Outcome results
None listed