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Correlation of MRI phenotypes and molecular characteristics in glioblastoma multiforme

Correlation of MRI phenotypes and molecular characteristics in glioblastoma multiforme

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OOC-14005289
Enrollment
Unknown
Registered
2014-10-02
Start date
2014-10-13
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glioblastoma multiforme

Interventions

GBM group:MRI

Sponsors

Department of Radiology, Institute of Surgery Research, Daping Hospital, Third Military Medical University
Lead Sponsor

Eligibility

Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Histopathological diagnosis of primary or recurrent GBM; (2) GBM without dissemination, age above 18 years old; (3) Newly diagnosed GBM without chemotherapy before surgery; recurrent GBM with complete therapeutic schemes and radiation dose; (4) Patients are provided written consent for the clinical data collection and the genetic analysis, according to national policies.

Exclusion criteria

Exclusion criteria: (1) Patients with multiple tumors; (2) Patients with meningoencephalitis or tuberculosis; (3) Pregnant Women (4) Patients with mental disorders; (5) Patients with diabetes cannot control the disease; (6) Patients with severe cardiopulmonary disease.

Design outcomes

Primary

MeasureTime frame
tumor volume;DNA copy number variation;mRNA expression profile;survival time;necrosis volume;peri-tumor edema volume;ADC value;NAA/Cr;Cho/Cr;Luc/Cr;rCBV;rCBF;MTT;TTP;Ktrans value;VSI value;tumor enhancing fraction;enhanced volume;enhanced volume/ necrosis volume;

Countries

Chongqing

Contacts

Public ContactWeiguo Zhang
wgzhang01@163.com+86 13908362993

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026