Sleep disturbance
Conditions
Interventions
control group:suppression of slow wave sleep for 1 night
insulin resistance group:suppression of slow wave sleep for 1 night
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
Male
Age
20 Years to 24 Years
Inclusion criteria
Inclusion criteria: (1) Body Mass Index is less than 25Kg/m2; (2) Age less than 35 years old; (3) No smoking or drinking habits, no long-term use of drugs; (4) subject should work and rest normally, sleep 7 to 9 hours every night, not on physical and mental stress, not on night shift and jet lag in recent six months.
Exclusion criteria
Exclusion criteria: (1) organic diseases were excluded by carefully medical history collection and biochemical screening; (2) impaired glucose tolerance or impaired fasting glucose were excluded by oral glucose tolerance test; (3) depression or other mental illness which may affect sleep were excluded by depression scale or specific screening methods if necessary; (4) the sleep quality of the subject was evaluated by the Epworth sleepiness scale and Pittsburgh sleep quality index, and polysomnography would be carried out to exclude sleep apnea if necessary.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glucose infusion rate;Slow wave activity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate variability;cortisol;inflammatory factor;other sleep monitoring parameters; | — |
Countries
China
Contacts
Public ContactAng Li
Outcome results
None listed