Non small cell lung cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Patients confirmed by pathology or cytology diagnosed as carcinoma in situ or with stage Ia non-small cell lung cancer; (2) Age between 18 and 80 years (including 18, 80); (3) The expected survival period over 1 year; (4) Karnofsky score more than 60 ; (5) Before the treatment, the Chinese Traditional medicine pieces or granules were not used in 3 months; (6) Patients voluntary participation in this study ,and can signed informed consent, and they can be followed up.
Exclusion criteria
Exclusion criteria: (1) Patients with severe disease, such as heart, liver and kidney, and its functional disorder; (2) Corticosteroids not used in the past 3 months; (3) Patients combined other immune disease; (4) 1 months after the chemotherapy or radiotherapy and chemotherapy and other cancer therapy are being conducted; (5) Pregnant or lactating women; (6) Patients cannot obey the rules of this research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immunoglobulin IgG;Immunoglobulin IgA;Immunoglobulin IgM;IFN-garma;IL-10;TGF-beta;VEGF;NK cells (CD3-CD56dimCD16+);NK cells (CD3-CD56brightCD16-);B cells (CD19+);T cell subsets (CD3+CD8+);T cell subsets (CD3+CD4+);T cell subsets (CD8+);T cell subsets (CD4/CD8+);Treg (CD4+CD25+Foxp3+);MDSC(CD11b+ Gr-1+); | — |
Secondary
| Measure | Time frame |
|---|---|
| CEA;AFP;CA125;CA153;CA199;CYFRA21-1;SCC;CTC; | — |
Countries
China