Keratoconus
Conditions
Interventions
Case series:1. UV-A 3mW : 30 minutes
2. 1% riboflavin: q2min x 15
Sponsors
Hong Kong Eye Hospital
Eligibility
Sex/Gender
All
Age
13 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Previously treated with accelerated CXL; 2. Progressive keratoconus after treatment, as defined by (1) worsened best-corrected visual acuity not accountable by corneal scarring (or other lenticular or posterior segment diseases), and/or (2) 1D increase in steepest curvature, >1D increase in manifest cylinder and >0.5D increase in manifest spherical equivalent observed at two consecutive occasions.
Exclusion criteria
Exclusion criteria: 1. Central ECD less than at least 2000; 2. Corneal pachymetry <400um at thinnest point (on Pentacam); 3. Corneal scarring; 4. History of corneal surgery, herpetic eye disease, severe DES, LSCD, delayed epithelial healing; 5. Underlying autoimmune disease, pregnancy, nursing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Topography: Kmax, Kmean, anterior elevation, posterior elevation; | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Visual acuity;2. Refraction;3. Endothelial cell density;4. Axial length;5. Pachymetry;6. Complications; | — |
Countries
China
Contacts
Public ContactDr. Chow Wing See Vanissa
Outcome results
None listed