Postoperative Cognitive Dysfunction
Conditions
Interventions
Case series:NA
Sponsors
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients aged 65-75 years presenting for major orthopaedic surgery (hip and knee arthroplasty) in Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology.
Exclusion criteria
Exclusion criteria: A score on the mini-mental state examination (MMSE) at screening of 23 or less; a disease of the central nervous system; were taking tranquillisers or antidepressants; had been admitted for neurological or cardiac surgery; previously undergone neuropsychological testing; were unwilling to comply with the protocol or procedures; had any severe visual or auditory disorders; were illiterate; had Parkinson's disease; alcoholism, or drug dependence; and if they were not expected to be alive for discharge from hospital after surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MiRN; | — |
Countries
China
Contacts
Public ContactXueren Wang
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed