Ventilator-associated lung barotrauma
Conditions
Interventions
Altogether 9 (groups) test (program), with the tab:On a fully experimental requirements, subject to 33 = 27 combinations of testing, and has not yet considered the number of repetitions of each combin
Each (group) test (program), repeated three times.:This orthogonal design analysis of variance, the error sum of squares retrieved from "repeated trials" (K = 3 ie n = 3 cases) rather than "empty colu
useing the Datex Ohmeda Aespire 7100 anesthesia v :No interaction between the three factors of breathing frequency (f), tidal volume (VT), inspiratory to expiratory ratio (I: E), using the anesthesia
Sponsors
Shanghai Pudong Hospital, Fudan University Pudong Medical Center
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.The ? - ? grade ,witch from the ASA (American Society of Anesthesiologists American Society of Anesthesiologists) assessment grading standards of patients .2.Obesity index (BMI) measured by the World Health Organization standard "30 = weight / height 2 <40"; 3.male or female, 18 years = Age = 65 years of age;4.subjects were informed, voluntary informed consent;5.Ventilator parameters: f = 15,12,9 (times / min), VT = 8,10,12 (ml / kg), I: E = 1:2.5,1: 2.0,1:1.5; 6.PETCO2 :35-45mmHg; SpO2 :99-100%; 7.used L9 (34) K = 3 repeat orthogonal experimental design and analysis table;8.used Dafex Ohmeda Aespire 7100 type of anesthesia ventilator; 9.optional Infinity Vista XL Dr?ger monitors.
Exclusion criteria
Exclusion criteria: 1.within a month before the start of the study had participated in other clinical trials were; 2.Within a month the upper respiratory tract infection were cured; 3.There ankylosing spondylitis, pulmonary fibrosis and other affected persons chest compliance; 4.determined lung disease patients; 5.patients with anemia; 6.There is depression neuropsychiatric tendencies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Table 1:setted the table of three factors and thre;World Health Organization recommended body mass in;Table 2: Repeatted orthogonal experimental design;An analysis of various table affectted PETCO2 from;Table4: An analysis of various table affectted PIP;Table5: An analysis of various table affectted Pme; | — |
Countries
China
Contacts
Public ContactZhanfang Li
Outcome results
None listed