Chronic hepatitis B, HBV related cirrhosis, hepatocellular carcinoma
Conditions
Interventions
Normal liver tissue and blood:Detect SST, SSTR, COX-2, HBx, AFP, etc.
Adjacent liver tissue of HCC and blood:Detect SST, SSTR, COX-2, HBx, AFP, etc.
Chronic hepatitis tissue and blood:Detect SST, SSTR, COX-2, AFP etc.
Cirrhotic liver tissue and blood:Detect SST, SSTR, COX-2, HBx, AFP, etc.
HCC tissue and blood:Detect SST, SSTR, COX-2, HBx, AFP, etc.
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients without chronic hepatitis, cirrhosis and carcinoma who require operation due to liver benign diseases; 2. Patients with chronic hepatitis B who require operation due to liver benign diseases; 3. Patients with HBV-related cirrhosis who require operation due to liver benign diseases; 4. Patients with hepatocellular carcinoma and chronic hepatitis B or HBV-related cirrhosis who require operation.
Exclusion criteria
Exclusion criteria: 1. Patiens with non-HBV related chronic hepatitis; 2. Patiens with non-HBV related cirrhosis; 3. Patients with non-HBV accociated hepatocellular carcinoma; 4. Patients with chronic liver diseases with mutiple etiology; 5. Patients who are not willing to receive operation or have any contraindications of operation; 6. Have received anti-viral or anti-neoplastic therapy,etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cycloxygenase-2;HBV X protein;Somatostatin receptor 1-5;Somatostatin;AFP etc; | — |
Countries
China
Contacts
Public ContactTang Cheng-Wei
Outcome results
None listed