ischemia stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1)the age of 18-80 years of age hospitalized patients;2)patients are diagnosed to acute ischemic infarction;3)meet thrombolysis criterion and agree to rt-PA treatment;4)Neurological deficit score (NIHSS) score of 4-25points; 5)Patients agree to sign clinical use informed consent;6)cooperate to medical history collection and follow-up.
Exclusion criteria
Exclusion criteria: 1)CT examinations indicate cerebral bleeding; 2) not meet thrombolysis criterion and agree to rt-PA treatment; 3)Associated pneumonia or other serious infections; 4) patients suffer from cardiac insufficiency, chronic liver disease(A/G inversion), ALT rising up to 1.5 times of normal value,blood creatinine elevating higher than 1.5 times of normal value or other serious systemic or organ organic diseases; allergic constitution, allergic history to various drugs; 5)Serum HIV, syphilis antibody positive, hepatitis b or hepatitis c patients;6)severe mental disorders, or existing other conditions who can not cooperate;7)Occurred malignancy or ongoing anti-tumor treatment; 8)pregnancy or lactating women; 9)participate in any other interventional clinical research in three months after obtaining informed consent, or is participating in other intervention clinical research; 10)other situation not suitable for clinical study of patients by the doctor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NIHSS score;permeability surface(PS);mRS score;mean transit time(MTT; | — |
Countries
China