Phase I/II study of different fractionation regimens of adjuvant radiation therapy in breast cancer patients after modified radical mastectomy

Status

Recruiting

Phases

Phase 2

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-ONRC-14004391

Enrollment

Unknown

Registered

2014-03-09

Start date

2009-05-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

1:42.6Gy/16F adjuvant irradiation

2:36.5Gy/16F adjuvant irradiation

Eligibility

Sex/Gender

Female

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Voluntary patients with written informed consent; (2) aged 18 to 75 years old; (3) undergoing modified radical mastectomy, and postoperative pathological diagnosis is invasive ductal carcinoma; (4) routine blood tests and liver and kidney functions are normal; (5) Karnofksy performance score more than 70; Life expectancy longer than 6 months; (6) without distant metastasis; (7) normal function of heart and lung.

Exclusion criteria

Exclusion criteria: (1) Distant metastasis; (2) With history of chest irradiation; (3) Active connective tissue diseases in treatment region; (4) Severe basic diseases: hypertension, cardiovascular disease, history of mental disease or allergy; (5) Refuse or unable to write informed consent; (6) Life expectancy shorter than 6 months.

Design outcomes

Primary

Measure	Time frame
Acute toxicities;Late toxicities;Loco-regional control;	—

Secondary

Measure	Time frame
Distant metastasis;	—

Countries

China

Contacts

Public ContactLin Ma

Department of Radiation Oncology, Chinese PLA General Hospital

malinpharm@sina.com+86 13911197589

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 20, 2026