postoperative patient controlled analgesia
Conditions
Interventions
R group:Performed femoral nerve blocking analgesia with 0.2% ropivacaine with total volume of 300ml
RS group:Performed femoral nerve blocking analgesia with the combination of 0.16% ropivacaine and 0.33 sulfentil with total volume of 300ml
PCIA group:patient controlled intravenous analgesia with administration of tramadol
Sponsors
First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients who would receive total knee replacement for any reasons, aged 18-80 years old, and with an ASA stage of I-III would be included in this study.
Exclusion criteria
Exclusion criteria: (1) with ASA stage over III; (2) body mass index over 35; (3) neural or mental disorder; (4) with coagulation dys-function, or active peptic ulcer or being receiving anticoagulation therapy; (5) with rheumatic arthritis in both knees or receiving revision for knee arthroplasty; (6) with infection at the scheduled puncture site for femoral nerve, or known allergic to substance would be administered; (7) uncontrolled systematic infection; (8)with cardiac arrest during surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ROM while discharge;WOMAC sores while discharge;VAS sores of pain while in hospital;Mortality of 30 days postoperativel; | — |
Secondary
| Measure | Time frame |
|---|---|
| Times of pressing PCA pump;Amount of drugs used for remedial analgesia;Incidence of adverse event after surgery;Average hospitalization days after surgery;NRS scores of pain when 3 ,6,and 12 months after;Mortality of 12 months postoperativel; | — |
Countries
China
Contacts
Public ContactMin Su
Department of Anesthesiology, the First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed