Squamous cell cancer of the larynx and hypopharynx
Conditions
Interventions
1:69Gy/30F radical IMRT
2:70Gy/33F radical IMRT
Sponsors
Department of Radiation Oncology, Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged from 18 to 75; 2. The pathological diagnosis is squamous cell carcinoma; 3. Patients diagnosed cancer of the larynx and hypopharynx are staged retrospectively from III to IV B, in accordance with the American Joint Committee on Cancer 2010 criteria. Or refuse operation; 4. Normal blood picture and hepatorenal function; 5. NO severe and /or uncontrolled medical conditions, including severe cardiovascular disease, uncontrolled diabetes and high blood pressure, active infection, liver and kidney disorders; 6. No second primary carcinoma; 7. Karnofsky scoring function from 60 to 100.
Exclusion criteria
Exclusion criteria: 1. Severe and /or uncontrolled medical conditions, including severe cardiovascular disease, uncontrolled diabetes and high blood pressure, active infection, liver and kidney disorders; 2. Patients in pregnant or nursing; 3. Received any surgical operation or radiotherapy; 4. Patient with uncontrollable mental disease and active infection; 5. Documented hypersensitivity reaction to paclitaxel or taxinol; 6. Patient with lower compliance; 7. Patient not fitted for this study determined by the principal investigator (PI).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ORR;PFS; | — |
Countries
China
Contacts
Public ContactLin Ma
Department of Radiation Oncology, Chinese PLA General Hospital
Outcome results
None listed