Neurofibromatosis type 2
Conditions
Interventions
therapeutic group:drug therapy
Sponsors
Beijing Tiantan Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
16 Years to 30 Years
Inclusion criteria
Inclusion criteria: 1) Patients must be at the age of 16-30; 2) Patients must meet the diagnostic criteria for NF2, with bilateral acoustic neuroma and other central nervous system tumors; 3) Patients must not be treated with other drugs or radiation therapy recently; 4) Patients should live in Beijing or nearby and can be treated in hospital; 5) Patients must be healthy and not be seriously allergic with biological agents; 6) Patients must join the clinical trial voluntarily, with good compliance, cooperate with the researchers well, sign a written informed consent.
Exclusion criteria
Exclusion criteria: 1) Treated with other drugs, surgery or radiation therapy recently; 2) Brainstem is compressed seriously, with hydrocephalus, need to be treated with surgery in short time; 3) Being pregnant or try to get pregnant, lactating women; 4) With acute or chronic infectious diseases; 5) With heart diseases, cardiac dysfunction or abnormal ECG; 6) With uncontrolled neural or mental diseases, poor compliance; 7) Not available for enhanced MRI; 8) Take part in any other clinical trial; 9) With other conditions that are considered not suitable for this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Volume of tumour;Hearing ability; | — |
Secondary
| Measure | Time frame |
|---|---|
| QOL score; | — |
Countries
China
Contacts
Public ContactLiu Pinan
Beijing Neurosurgical Institute
Outcome results
None listed