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Effect of pneumoperitoneum on the course of neuromuscular block following a single bolus dose of rocuronium during laparoscopic surgery

Effect of pneumoperitoneum on the course of neuromuscular block following a single bolus dose of rocuronium during laparoscopic surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ONRC-13003722
Enrollment
Unknown
Registered
2013-10-21
Start date
2013-10-12
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gynecologic surgery

Interventions

Two groups:laparoscopy vs open surgery

Sponsors

The Obstetrics and Gynecology Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Female patients, ASA I–II, aged 18–60 years and with a body mass index (BMI) of 18-30 kg/m*2 requiring elective gynecologic operation under general anesthesia were included. According to different surgical procedures, all patients were divided into two groups: patients in open surgery group (Group 1); patients in laparoscopic surgery group (Group 2).

Exclusion criteria

Exclusion criteria: Specifically, the patients with cirrhosis, hepatitis, hepatoma, heart failure or arrhythmia, renal dysfunction (defined as a creatinine clearance of =30 mL/min), water-electrolyte disturbances, acid-base imbalances or neuromuscular disorders were excluded from the study. None of the patients was receiving medications known to interfere with neuromuscular blocking agents, such as antibiotics and anticonvulsants. Patients with anticipated difficult intubation (Mallampati score [11] III and more) were also excluded.

Design outcomes

Primary

MeasureTime frame
Neuromuscular Monitorin;

Countries

China

Contacts

Public ContactWang Tingting

Department of Anesthesia, Shanghai Obstetrics and Gynecology

ti3wt@163.com+86 13564419229

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026