Thyroid Nodule
Conditions
Interventions
RFA:Radiofrequency ablation
LA:Laser ablation
MWA:MWA ablation
Sponsors
Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: (meet all of the following conditions can be selected) 1. nodule or predominantly (>20%)solid nodule; 2. maximum diameter of the nodule > 2cm; 3. nodules did not undergo other treatments (such as: radioactive iodine therapy, TSH suppressive therapy, ethanol ablation); 4. the pathologic result of 2 times needle aspiration or core needle biopsy is benign; 5. inoperable due to the patient's bad body conditions or refused to surgery; 6. nodules according to one of the following items below: (1) nodules increased significantly (volume increases more than 50% within 1 year,or at least two diameters of the nodule increase over 20% and it more than 2 mm long]); (2) patients with nodules significantly related symptoms (such as: foreign body sensation, neck discomfort or pain); (3) nodules obviously convex affect the appearance and require treatment; (4) ideological concerns of patients too heavy to affect normal life and denial of clinical observation; (5) autonomously functioning nodules caused symptoms of hyperthyroidism.
Exclusion criteria
Exclusion criteria: Exclusion criteria: (excluding comply with any of the following items) 1. the follicular nodules or biopsy suggest the malignancy; 2. the founction of contralateral vocal cord is not abnormal; 3. severe coagulation disorders; 4. severe cardiac or pulmonary disease; 5. refused to participate in this research or refused to sign an informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| volume reduction rate;Cosmetic score;Symptom score;vascularity scale;therapeutic success rate (volume);recurrence rate;complication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| radiology examination;LOS(length of stay);operative time;parameters of in ablation;thyroid function; | — |
Countries
China
Contacts
Public ContactPing Liang, Zhi-gang Cheng
Outcome results
None listed