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A clinical study for effect of various treatments on different types of gallstone pancreatitis

The protective mechanism of lipoxin A4 in the pancreatitis associated lung injury model: tumor necrosis factor mediated inflammatory pathways and death pathway

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ONRC-12002671
Enrollment
Unknown
Registered
2012-11-03
Start date
2007-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute gallstone pancreatitis

Interventions

?1:ERCP+EST
?2:Conservative Treatment
?3:Late operation
?4:Early operation
?1:Late operation
?2:Early operation
?1:Conservative Treatment
?2:Late operation
?3:Early operation
?4:Regional arterial infusion

Sponsors

The First Affiliated Hospital of Wenzhou Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to 92 Years

Inclusion criteria

Inclusion criteria: 1. All patients must meet the diagnostic criteria for gallstone pancreatitis diagnosis: 1) have the clinical manifestations of acute pancreatitis; 2) the serum amylase is higher than normal limit 3 times above; 3) B ultrasound, CT examination confirmed biliary calculus in biliary tract; 4) AST/ALT levels or serum bilirubin rise; 5) does not exist other causes lead to serum amylase, AST/ALT and bilirubin increase. 2. Biliary obstruction person should have one of the following two conditions: 1) clinical Charcot triple signs or Reynold quintuplet signs; 2) the image examinations discover common bile duct expanding (diameter > 1.0 cm) or combined with intrahepatic bile ducts dilation, and total bilirubin > 40.0 umol/L, direct bilirubin/total bilirubin > 50%. 3. Mold and severe acute pancreatitis classification standard is according to Atlanta classification: severe AP refers to the AP associated with organ dysfunction, or pancreas necrosis, abscess or pseudocyst local complications or both.

Exclusion criteria

Exclusion criteria: 1) Patients who are long-term suffering from chronic diseases and poorly controlled, such as diabetics, liver cirrhosis patients, patients after all kinds of transplantation; 2) During the hospital time, patients has noting to do with other diseases need to therapy,such as with varicose vein of lower limb need surgery, cardiovascular diseases need intervention therapy the patient; 3) GP occurred in hospital stay; 4) Patients lack of CT data; 5) Patients against medical ad; 6) Patients can not follow-up visit.

Design outcomes

Primary

MeasureTime frame
A period cure rate;Recurrence rate;Complication rate;Clavien-Dindo Grade;The mean hospital stay;Average hospitalization expense;Ranson Grade;

Countries

China

Contacts

Public ContactZhou Mengtao
zmt0417@hotmail.com+86 13806697558

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026