Prolapse of Lumbar Intervertebral Disc
Conditions
Interventions
A:Discectomy
B:Lumbar Interbody Fusion
C:Discectomy combined with non-fusion internal fixation (Dynesys, K-Rod, Isobar, Bioflex)
Sponsors
Hospital of Third Military Medical University, PLA
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 60 years; 2. Patients who have symptoms such as low back pain, leg pain and/or tingling and lower extremity weakness which obviously affect daily life and work; 3. Patients whose radiological outcomes indicate prolapse of lumbar intervertebral disc; 4. Patients whose symptoms aren’t obviously improved with strict and standard conservative treatment more than 1 month.
Exclusion criteria
Exclusion criteria: 1. Large herniation of lower lumbar intervertebral disc combined with cauda equina syndrome; 2. Adjacent level degeneration(The principal findings on radiological outcomes are osteophytes, lumbar instability, the height loss of involved disc space, black disc, and degenerate intervertebral joint); 3. Patients who combine with other lumbar lesions such as lumbar spondylolisthesis, lumbar spondylolysis, spinal stenosis, discogenic low back pain, spinal organic deformity, spine fracture, ankylosing spondylitis, tuberculosis of spine, Spinal infection and spinal tumor, and cervical diseases; 4. Patients who need second operation with recurrent disc herniation and adjacent level herniation; 5. Patients who have trauma and diseases of lower extremity joint, muscles and nervus which affect the function of lower extremity; 6. Osteoporosis patients(BMD<2.0s); 7. Patients who combine with trauma and diseases of nervous system; 8. Patients who combine with other systemic diseases; 9. Psychotic patients; Pregnant women or women planning to get pregnant during the study period; Has a history of substance abuse (recreational drugs, alcohol); 10. Is currently involved in another study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oswestry disability index;Visual analog scale;Macnab classification;ROM of lumbar;Recurrent disc herniation or no; | — |
Secondary
| Measure | Time frame |
|---|---|
| Woodend classification;Operation time;Blood loss during operation;Hospitalization time; | — |
Contacts
Public ContactQiang Zhou
Outcome results
None listed