Effects of intensive treatment of Statin Towards atherosclerosis plaques in patients with borderline vulnerable plaque lesion

Effects of different treatment of atorvastatin towards atherosclerosis plaques in patients with unstable angina

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-ONRC-12002035

Enrollment

Unknown

Registered

2012-03-21

Start date

2008-08-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary heart disease

Interventions

Moderation Group/Intensity Group:atorvastatin intensive treatment

Eligibility

Sex/Gender

All

Age

30 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. In the age 30-75 years old, male or female; 2. unstable angina.Diagnosis standard basis treatment guidelines of ACC/AHA on unstable angina pectoris/the st-elevation myocardial infarction; 3. required coronary angiography and one 50%-70% stenosis plaque was selected as target plaque in each patient.

Exclusion criteria

Exclusion criteria: 1. Age more than 75 years old.Weighing less than 50 kg; 2. Also with a variety of diseases; 3. with severe hepatic or renal insufficiency, Especially of diabetic nephropathy; 4. Serious infection, perioperative and shock; 5. Combined application of Ciclosporin, Verapamil, Amiodarone; 6. have myopathy or unexplained muscle acid phosphorus enzyme heighten; 7. already treated with statins.

Design outcomes

Primary

Measure	Time frame
Plaque Volume;Vessel Volume;Lumen Volume;	—

Countries

China

Contacts

Public ContactQiujianping

qiujianping1005@hotmail.com+86 15921911149

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026