Essential Hypertension
Conditions
Interventions
Female A:Felodipine Sustained Release Tablets + Irbesartan
Female B:Felodipine Sustained Release Tablets + Metoprolol
Male A:Felodipine Sustained Release Tablets + Irbesartan
Male B:Felodipine Sustained Release Tablets + Irbesartan
Sponsors
The Second Hospital of Lanzhou University
Eligibility
Sex/Gender
Male
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients with essential hypertension;Initial hypertension, or without taking any antihypertensive for at least one month; Sexual active.
Exclusion criteria
Exclusion criteria: Patients with secondary hypertension. Patients with malignant hypertension, coronary heart disease, diabetes, a history of syncope, bradycardia (heart rate <45 beats/min), atrioventricular block (II or III degree), sick sinus syndrome, congestive heart failure, a history of cerebral vascular accidents, serious hepatic and kidney dysfunction, a history of serious mental illness, pregnant, taking oral exogenous estrogens (including contraceptives), hysterectomy, breastfeeding, a history of alcohol or drug abuse, having serious conflict with sexual partner, severity sexual dysfunction. Refused to answer questions, refuse to fill in the questionaire, or do not want to take blood examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum 4-HNE;Femal Sexual Fuction Index(FSFI);International Index of Erectile Function(IIEF-5); | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum MDA;Serum Estradiol;Serum 8-OHdG;Change of Systolic Pressure;Serum Testosterone;Change of Diastolic Pressure; | — |
Countries
China
Contacts
Public ContactJing Yu
Outcome results
None listed