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research of genetic gene and immune state in Ankylosing Spondylitis

research of genetic gene and immune state in ankylosing spondylitis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ONRC-11001565
Enrollment
Unknown
Registered
2011-09-16
Start date
2009-06-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ankylosing Spondylitis

Interventions

AS patients:None
Healthy control:None

Sponsors

Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients had to meet the modified New York clinical criteria in 1984 for definite ankylosing spondylitis; 2. Patients can provid the informed consent document in writing, and agree to abide by the requirement for the of the research plan.

Exclusion criteria

Exclusion criteria: 1. Female patients who are pregnant or breastfeeding; 2. Patients who have severe systemic disease; no perceptibility or can not take care of oneself in daily life; malignant tumor.

Design outcomes

Primary

MeasureTime frame
expression of associated microRNA;expression of HLA-B27 gene;expression of AS associated gene;

Secondary

MeasureTime frame
Treg cell quantity;TH1 cell quantity;TH17 cell quantity;expression of associated microRNA;

Contacts

Public ContactPing Zhu
zhuping@fmmu.edu.cn+86 029-84775355

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026