Combined liver-pancreas en-bloc transplantation in patients with end-stage liver disease and insulin dependent type2 diabetes mellitus: a multicenter, prospective, matched pair study (LPILDStudy)

Combined liver-pancreas en-bloc transplantation in patients with end-stage liver disease and insulin dependent type2 diabetes mellitus: a multicenter, prospective, matched pair study

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-ONRC-11001563

Enrollment

Unknown

Registered

2011-09-21

Start date

2011-10-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic liver diseases and liver cirrhosis

Interventions

OCT group:Combined liver-pancreas en-bloc transplantation

Control group:Liver transplantation only without pancreas transplantation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. The informed consent signed; 2. Aged 18-65 years old; 3. End-stage liver disease and insulin dependent type2 diabetes mellitus patients

Exclusion criteria

Exclusion criteria: 1. Severe cardiac or renal dysfunction; 2. ABO blood type incompatibility; 3. Cold ischemia time of allograft longer than 12 hours or warm ischemia time longer than 15 mins; 4. Large blood vessels(PV, HV or IVC) invaded by HCC. 5. Follow-up not conducted in the institute of transplantation.

Design outcomes

Primary

Measure	Time frame
Blood glucose control: HbA1C, MAGE and SDBG;Diabetic microvascular complication: MER;	—

Secondary

Measure	Time frame
Rates of transplant complications like rejection and vascular complications;Diabetic neuropathy;Diabetic microvascular complication;Diabetic macrovascular complication;5-year survival;	—

Countries

China

Contacts

Public ContactXiaoshun He

gdtrc@163.com+86 13802510799

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026