primary depression
Conditions
Interventions
Group of healthy volunteers:reveive electro-acupuncture at Yintang (EX-HN3) and Baihui (DU20) for 30 min. Before and after the needling, all the volunteers receive the resting cerebral functional magn
Group of depression patients:reveive electro-acupuncture at Yintang (EX-HN3) and Baihui (DU20) for 30 min. Before and after the needling, all the volunteers receive the resting cerebral functional mag
Sponsors
Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for the Healthy volunteers: (1) non-medical students with the ages of 21-28 years old; (2) regular diet, no propensity with alcoholic, tobacco , coffee and tea, normal sleep and moderate body weight; (3) Right handedness. (4) be informed and sign the informed consent. Inclusion criteria for the depression patients: (1) 18 to 60 years old; (2) being diagnosed with the "International Classification of Diseases and diagnostic criteria", except bipolar depression and secondary depression. The score of Hamilton Depression Rating Scale (HAMD) more than 17 and less than 24; (3) sign the informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria for healthy volunteers: (1) had mental or nervous system disease history; (2) suffered all types of pain (including dysmenorrheal), depression, and other physical and mental symptoms around the trail (1months); (3) received acupuncture treatment in the recent 1 month; (4) with congenital, tumors and vascular disorders in the central nervous system; (5) whole-body metabolism disorder, immune disease and peripheral neuropathy; (6) with serious heart, liver and kidney disease, endocrine or blood disease; (7) thrombocytopenia, hemophilia, coagulation disorder; (8) history of taking mental drugs; (9) metals like substances in the body; (10) having claustrophobia Depression patients should be excluded: (1) having cerebral disease and serious disease of other systems which need treatment; (2) Having antidepressants or pharmacological effects of antidepressants do not have elution period; (3) No other clinical test in last four weeks; (4) Having suicidal plans or actions; (5) Pregnant women and breast-feeding women and patients unfitted to acupuncture; (6) having claustrophobia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| regional homogeneity;amplitude low- frequency fluctuation; | — |
Countries
China
Contacts
Public ContactYong Huang
Outcome results
None listed