obesity and its related diseases
Conditions
Interventions
AE:aerobic exercise intervention
NC:normal control
OC:positive control without intervention
DE:diet and aerobic exercise intervention
D:diet intervention
Sponsors
Beijing Hospital of Ministry of Health
Eligibility
Sex/Gender
All
Age
12 Years to 16 Years
Inclusion criteria
Inclusion criteria: BMI above the 85th percentile for overweight, and normal BMI for normal control; age from 12 to 16 years old, no limit on sex; good compliance, willing to sign the inform consent
Exclusion criteria
Exclusion criteria: Secondary obesity; diagnosed diabetes and heart, brain, lung, kidney and movement system diseases; Alt over two times of normal range; acute stress condition within one month; progressive fatal disease; alcohol and drug abuse; chronic disease receiving treatment; history of mental disease; can't finish the follow-up or poor compliance; unwilling to sigh the inform consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| expression of NOX subunits;BMI, body fat percentage;serum glucose, TC and LDL-c, MDA, protein carbonyl and ROS in monocytes; | — |
Secondary
| Measure | Time frame |
|---|---|
| circumferences of chest, waist and hip, muscle mass, bone density;VO2max, Vital Capacity, Heart rate after exercise; | — |
Countries
China
Contacts
Public ContactXie Minhao
Outcome results
None listed