Ovarian Cancer
Conditions
Interventions
Control Group:(Paclitaxel + cisplatin) intravenous chemotherapy
Group 1:(Paclitaxel + cisplatin) intravenous chemotherapy plus arterial infusion of cisplatin (the second, fourth and sixth cycle)
Sponsors
The Obstetrics & Gynecology Hospital of Fudan University
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) 100 cases of advanced ovarian cancer (stage III - IV) treated by tumor reduction surgery and confirmed by pathology; 2) before the study, we did not receive any treatment related to this disease, including surgery, hormone therapy (cyclical treatment, etc.), chemotherapy, radiotherapy and other antitumor drugs. There was no contraindication between intravenous chemotherapy and interventional chemotherapy; 3) the signing of the informed consent; 4) any one in conformity with the following exclusion criteria is not included.
Exclusion criteria
Exclusion criteria: 1) patients with advanced ovarian cancer are in a life - threatening emergency; 2) the combination of other malignant diseases; 3) younger than 18 years) or elderly (over 70 years) or for other reasons can't sign the informed consent, and no other guardian agent; 4) mental illness or psychological illness, unable to cooperate with the experimenter; 5) need to hide the disease for the patient; 6) take part in other clinical trials at the same time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CA125;immunohistochemistry;HE4;ultrasonography;time to live;Liver and kidney function; | — |
Countries
China
Contacts
Public ContactLiangqing Yao
The Obstetrics & Gynecology Hospital of Fudan University
Outcome results
None listed