blepharitis associated keratoconjunctivitis
Conditions
Interventions
OPT group:optimized pulsed light technology
Control group:Meibomian gland expression
Sponsors
Beijing Tongren Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) at least 18 years old of age; (2) both eyes were affected; (3) with signs of blepharitis including eyelid hyperemia or capillary dilation, scale, scab or ulcer of eyelash root, morphologic changes of Meibomian gland; (4) concomitant conjunctival and corneal lesions: conjunctival congestion, papillary hyperplasiafollicular formation or blister conjunctivitis; and corneal peripheral punctate erosions, infiltration or ulceration, or corneal opacity with neovascularization.
Exclusion criteria
Exclusion criteria: (1) acute inflammation or allergies of the eye or periocular skin; (2) diseases that can be triggered by light wave from 560nm to 1200nm in length, such as recurrent herpes simplex infection, systemic lupus erythematosus and Porphyria; (3) pregnant or lactating; (4) treated with radiotherapy or chemotherapy within 1 year prior to the study or scheduled to undergo radiotherapy or chemotherapy within 2 months after OPT treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| quality of meibum scoring;expressility of meibum scoring;changes of eyelid margin scoring; | — |
Secondary
| Measure | Time frame |
|---|---|
| corneal fluorescein staining scoring;ocular surface disease index scoring;noninvasive keratography break-up time; | — |
Countries
China
Contacts
Public ContactJie Ying
Beijing Tongren Hospital, Capital Medical University
Outcome results
None listed