Primary Meige syndrome
Conditions
Interventions
control group:Botulinum toxin type A injection
Sponsors
Bei Jing Tong Ren hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
35 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with primary Meige syndrome; 2. Patients who have failed to effectively control symptoms and seriously affect quality of life through botulinum A toxin treatment; 3. Good health conditions except the symptoms of dystonia; 4. The results of the simple mental state scale (MMSE) screening were normal; 5. The subjects or their families can fully understand the therapy and sign the informed consent; 6. The subjects have good compliance and can cooperate with the follow-up requirements after the operation.
Exclusion criteria
Exclusion criteria: 1. Imaging examination of patients with abnormal changes in the basal ganglia; 2. Patients had a serious progressive nervous system, a cardiovascular system, a respiratory system, or a digestive system disease; the patient's mental state is unstable; 3. Patients have surgical or anesthetic contraindications, such as long-term anticoagulant, antiplatelet drugs, etc; 4. Women who are planning to be pregnant, or are in pregnancy and breast-feeding; 5. Patients had or needs other implants, such as the cardiac pacemaker, defibrillator, cochlear, and the root electric stimulator; 6. Patients need multiple 3.0T MRI tests during future clinical trials for their own reasons; 7. Patient had taken part in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Burke-Fahn-Marsden DystoniaRating Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse reaction and Quality of life scale;HAMA and HAMD Scale; | — |
Countries
China
Contacts
Public ContactFu Jing
Bei Jing Tong Ren hospital, Capital Medical University
Outcome results
None listed