Transient Ischemic Attack
Conditions
Interventions
Control:expansion only, oral antiplatelet or anticoagulant therapy
Sponsors
Da Ping Hospital of Third Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) =18 years old, no intracerebral hemorrhage, no visible arterial occlusion on the CTA or MRA; 2) Patient or his/her relative is willing to participate in the study and to provide informed consent; 3) Symptoms recurred at least three times in 24 hours, but continued less 1 hour per time. Symptoms affected at least included two parts among face, arm, and leg.
Exclusion criteria
Exclusion criteria: 1) The last episode continued more than 1 hour but less than 4.5 hours when arrived the hospital; 2) Pre-stroke mRS = 2; 3) History of severe bleeding or major surgery within 30 days; 4) Coexistent terminal illness with life expectancy = 12 months; 5) Any known hereditary or acquired hemorrhagic diathesis, coagulation factor deficiency, or taking oral anticoagulant with INR > 1.7; 6) Platelet count < 100,000/mm3; 7) Hemoglobin < 10 g/dL; 8) A serum glucose level= 50 mg/dl; or 9) Severe renal insufficiency with creatinine clearance rate <30ml/min; 10) Patient or his/her relative refused to use tirofiban.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intracerebral hemorrhage transformation;NIHSS score;mRS;times of the reccurrent ischemic events; | — |
Countries
China
Contacts
Public ContactMeng Zhang
Neurology Department of Daping Hospital, Third Military Medical University
Outcome results
None listed